Allergy
Immunology
Atopy:
Allergy = Specific IgE and clinical symptoms
Atopic march = progression from eczema as an infant to allergic rhinitis and asthma
Atopy:
- genetic predilection to produce specific immunoglobulin E (IgE) following exposure to allergens
- Th2 (CD4+) response > secrete large quantities of IL-4 and IL-13 > promotes the production of allergen-specific IgE by plasma cells
Allergy = Specific IgE and clinical symptoms
Atopic march = progression from eczema as an infant to allergic rhinitis and asthma