Respiratory Failure
Each time there is worsening of failure circle round again
Obstruction
- Bronchoconstriction (asthma treatment)
- Plugging (hypertonic saline, chest physiology)
- Pneumothorax
- Haemothorax
- Hydrothorax
- Chylothorax
- ?Drainage
- TPN > Portagen feeds (no LC triglycerides)
- Effusion
- Transudate
- Exudate
- Empyema
Carriage
- CO poisoning (increased carboxyhaemaglobin)
- 240 x affinity for Haem than O2
- also causes change in Haem to prevent O2 offload from the other 3 sites
- BUT carboxyhaemaglobin not well correlated with toxicity because cellular respiration if the major defect
- also impairs oxidative phosphorylation at the peripheral cell at cytochrome c oxidase level (?binding cytochrome A3)
- also causes Delayed Neurologic Sequelae (DNS)
Rx
Needle thoracocentesis
Chest drain
Hypertonic saline
Bronchodilators
Oxygen
Noninvasive ventilation
I+V
?ECMO