Anaphylaxis
Immunology
Hypersensitivity
Most anaphylaxis is in preschoolers
BUT most deaths are in adolescents
Anaphylactoid is non IgE mediated direct mast cell activation anaphylaxis
Idiopathic anaphylaxis is non IgE, non direct mast-cell anaphlaxis
Complications
Kounis Syndrome (coronary artery vasospasm causing myocardial infarct)
Takotsubo syndrome (stress cardiomyopathy)
Ix
Trypase x1 1 hour apart
Troponin / ECHO if cardiac symptoms
Rx
Adrenaline IM (nb may need to balance risk as could worsen Kounis/Takotsubo)
Antihistamine PO
Steroid PO IF ingestion OR Hx asthma
Anaphylaxis Action Plan
Adrenalin Autoinjector
Factsheet on Allergen
?Dietitian
Food preparation
Hypersensitivity
- Difficulty/noisy breathing,
- swelling of the tongue
- swelling or tightness in the throat,
- difficulty talking and or hoarse voice,
- wheeze or persistent cough,
- persistent dizziness or collapse, pale and floppy (in young children)
Most anaphylaxis is in preschoolers
BUT most deaths are in adolescents
Anaphylactoid is non IgE mediated direct mast cell activation anaphylaxis
Idiopathic anaphylaxis is non IgE, non direct mast-cell anaphlaxis
Complications
Kounis Syndrome (coronary artery vasospasm causing myocardial infarct)
Takotsubo syndrome (stress cardiomyopathy)
Ix
Trypase x1 1 hour apart
Troponin / ECHO if cardiac symptoms
Rx
Adrenaline IM (nb may need to balance risk as could worsen Kounis/Takotsubo)
Antihistamine PO
Steroid PO IF ingestion OR Hx asthma
Anaphylaxis Action Plan
Adrenalin Autoinjector
Factsheet on Allergen
?Dietitian
Food preparation
- Only eat food prepared at home or with a food label that you can check
- don't use serving utensils that are also used to serve food containing egg