Vitamin D
Endocrinology
Hormone
(not vitamin as can be synthesised)
Inactive Vit D
Dietary intake recommendations assume nil synthesis in skin
No duration of sun exposure given skin cancer risk
Insufficiency leads to rickets/osteomalacia
Hormone
(not vitamin as can be synthesised)
Inactive Vit D
- Cholecalciferol = Vit D3 (ingested and synthesised in skin: cholesterol > Vit D3 by UVB)
- Ergocalciferol = Vit D2 (ingested)
- Cholecalciferol > 25-hydroxycholecalciferol aka calcifediol (by liver)
- ergocalciferol > 25-hydroxyergocalciferol (by liver)
- 1,25-dihydroxycholecalcifero AKA Calcitriol = Activated Vit D (by kidneys)
- increased renal resorption (main effect), gut absorption, and bone release
Dietary intake recommendations assume nil synthesis in skin
No duration of sun exposure given skin cancer risk
Insufficiency leads to rickets/osteomalacia