Pharmacodynamics
to Pharmacology
Action of drug on body (how it changes you)
- Mechanism of action (receptor/cellular)
- Therapeutic window / titration / Minimum Inhibitory Concentration
Action of drug on body (how it changes you)
- Mechanism of action (receptor/cellular)
- Therapeutic window / titration / Minimum Inhibitory Concentration
- Therapeutic (safety) Window = TD50 (50th centile toxic dose) / ED50 (efficacious)
- MIC (time above the MIC is the important factor)
- first order cytotoxicity = for a particular dose a fixed percentage of cells are killed