Neurodegenerative disorders
Etiology:
Hallmark is regression and progressive deterioration
loss of
feeding difficulties
impairment of intellect
UMN signs > white matter
Seizures, visual and intellectual impairment > grey matter
Usually fatal but diagnosis important for genetic counselling (CVS/Amnio)
- Genes
- Biochemical
- Chronic viral
- other
Hallmark is regression and progressive deterioration
loss of
- speech
- vision
- hearing
- locomotion
feeding difficulties
impairment of intellect
UMN signs > white matter
Seizures, visual and intellectual impairment > grey matter
Usually fatal but diagnosis important for genetic counselling (CVS/Amnio)